Left atrial thrombus after appendage closure using LARIAT.

Hemostasis of Left Atrial Appendage Bleed With Lariat Device

New devices designed for minimally invasive closure of the left atrial appendage (LAA) may be a viable alternative for patients in whom anticoagulation is considered high risk. The Lariat (Sentreheart, Redwood City, CA), which is currently FDA-approved for percutaneous closure of tissue, requires both trans-septal puncture and epicardial access. However it requires no anticoagulation after the ...

Where We Stand on Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation.

PURPOSE OF REVIEW Anticoagulant therapy effectively reduces the incidence of stroke in patients with atrial fibrillation (AF) but is underutilized and frequently contraindicated. The left atrial appendage (LAA) is the primary site of thrombus formation in AF patients. Surgical and percutaneous appendage closure has been evaluated as a site-specific therapy to reduce systemic thromboembolism. ...

Left Atrial Appendage Remodeling After Lariat Left Atrial Appendage Ligation.

BACKGROUND Left atrial appendage (LAA) ligation with the Lariat device is being used for stroke prevention in atrial fibrillation. Residual leaks into the LAA are commonly reported after the procedure. Little is known about the anatomic LAA remodeling after Lariat ligation. METHODS AND RESULTS In an exploratory study, we evaluated LAA 3-dimensional geometry via computed tomographic scan in 31...

Anatomic analysis of the left atrial appendage after closure with the LARIAT device.

Percutaneous Closure of a Residual Left Atrial Appendage Leak After Lariat Procedure.

A 77-year-old man with long-standing persistent atrial fibrillation, coronary artery disease, and systolic heart failure underwent left atrial appendage (LAA) ligation with a Lariat suture delivery device (SentreHEART, Redwood City, California), and subsequent pulmonary vein isolation. One month after the ligation procedure, transesophageal echocardiogram (TEE) demonstrated a residual communica...